Alyssin
Alyssin, found in Cruciferous Vegetables, exerts anticancer activity in HepG2 by increasing intracellular reactive oxygen species and tubulin depolymerization[1].
Product Specifications
CAS Number
[646-23-1]
UNSPSC
12352211
Hazard Statement
H225-H350
Target
Microtubule/Tubulin; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alyssin.html
Solubility
10 mM in DMSO
Smiles
O=S(C)CCCCCN=C=S
Molecular Formula
C7H13NOS2
Molecular Weight
191.31
Precautions
P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P405-P501
References & Citations
[1]Pocasap P, et al. Alyssin and Iberin in Cruciferous Vegetables Exert Anticancer Activity in HepG2 by Increasing Intracellular Reactive Oxygen Species and Tubulin Depolymerization. Biomol Ther (Seoul) . 2019;27 (6) :540-552.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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