Rilmakalim
Product Specifications
UNSPSC Description
Rilmakalim (HOE 234) is a potassium channel opener (PCO) that activates ATP-sensitive K+ channels in the heart or other tissues[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rilmakalim.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCC1)[C@H]2[C@@H](C(C)(OC3=C2C=C(C=C3)S(=O)(C4=CC=CC=C4)=O)C)O
Molecular Weight
401.48
References & Citations
[1]Kocic, Ivan
et al. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to
activate ATP-sensitive K(+) current in guinea pig ventricular myocytes. Journal
of pharmacological sciences vol. 95,2 (2004): 189-95.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116556/Rilmakalim-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116556/
Clinical Information
Phase 1
CAS Number
132014-21-2
Curated Selection
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