Amfonelic acid
Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter[1].
Product Specifications
CAS Number
[15180-02-6]
Product Name Alternative
WIN-25978
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/amfonelic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CN(C2=NC(CC3=CC=CC=C3)=CC=C2C1=O)CC
Molecular Formula
C18H16N2O3
Molecular Weight
308.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Aceto MD, et al. Pharmacologic properties and mechanism of action of amfonelic acid. Eur J Pharmacol. 1970;10 (3) :344-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
