Complex III-IN-2

Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor. Complex III-IN-2 shows antifungal activity with an EC50 of 29.98 mg/L and 29.31 mg/L against sclerotinia sclerotiorum and R. solani, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Fungal; Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/complex-iii-in-2.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(Cl)N=C1)(NC/C=C(C)/CC/C=C(C)\C)=O

Molecular Formula

C15H21ClN2O2S

Molecular Weight

328.86

References & Citations

[1]Song, X., et al. Synthesis, antifungal activity, and molecular dynamics study of novel geranyl aromatic sulfonamide compounds as potential complex III inhibitors. Med Chem Res 31, 628–642 (2022) .