TMC-205
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter[1].
Product Specifications
CAS Number
[403646-00-4]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tmc-205.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O
Molecular Formula
C14H13NO2
Molecular Weight
227.26
References & Citations
[1]Gao Y, et al. Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter. ACS Med Chem Lett. 2014;5 (8) :863-867. Published 2014 Jun 23.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114646/TMC-205-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114646/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
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