Asobamast

Asobamast is a potent, orally active antiallergic agent that inhibits ige mediated passive pulmonary allergic responses in rats (ED50=4.7 mg/kg) and inhibits antigen-induced mediator release from sensitized guinea pig lung fragments[1].

Product Specifications

CAS Number

[104777-03-9]

UNSPSC

12352005

Target

TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/asobamast.html

Solubility

10 mM in DMSO

Smiles

O=C(C(OCCOCC)=O)NC1=NC(C2=CC(C)=NO2)=CS1

Molecular Formula

C13H15N3O5S

Molecular Weight

325.34

References & Citations

[1]D Chiarino, et al. N- (4-Isoxazolylthiazol-2-yl) oxamic acid derivatives as potent orally active antianaphylactic agents. J Med Chem. 1991 Feb;34 (2) :600-5.