AcLysValCit-PABC-DMAE-SW-163D
Product Specifications
UNSPSC Description
AcLysValCit-PABC-DMAE-SW-163D is a agent-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SW-163D-AcLysValCit-PABC-DMAE.html
Solubility
10 mM in DMSO
Smiles
C[C@H](NC1=O)C(N([C@H](C(N([C@]2(C(OC[C@@H](NC(C3=C(C=C4C(C=CC=C4)=N3)O)=O)C(N[C@H](C(N(C)[C@@H](CS5)C(N(C)[C@]6(C(OC[C@H]1NC(C7=C(C=C8C(C=CC=C8)=N7)OC(N(CCN(C(OCC9=CC=C(C=C9)NC([C@@H](NC([C@@H](NC([C@@H](CCCCN)NC(C)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)C)C)=O)=O)=O)[C@H](C6)C)=O)=O)C)=O)=O)[C@H](C2)C)C)=O)[C@H]5SC)C)=O
Molecular Weight
1817.05
References & Citations
[1]Ratnayake AS, et al. Natural Product Bis-Intercalator Depsipeptides as a New Class of Payloads for Antibody-Drug Conjugates. Bioconjug Chem. 2018 Dec 13. doi: 10.1021/acs.bioconjchem.8b00843.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114325/AcLysValCit-PABC-DMAE-SW-163D-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114325/
Clinical Information
No Development Reported
CAS Number
2411007-69-5
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