11-trans Leukotriene E4
11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4) . Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum[1].
Product Specifications
CAS Number
[75715-88-7]
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/11-trans-leukotriene-e4.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O
Molecular Formula
C23H37NO5S
Molecular Weight
439.61
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]S Hammarström, et al. Metabolism of leukotrienes. Mol Cell Biochem. 1985 Nov;69 (1) :7-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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