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Uridine 5'-diphosphate-13C9,15N2 (dilithium)

Product Specifications

UNSPSC Description

Uridine 5'-diphosphate-13C9,15N2 dilithium is 13C and 15N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.

Target Antigen

Endogenous Metabolite; Isotope-Labeled Compounds; P2Y Receptor

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein;Metabolic Enzyme/Protease;Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/uridine-5-diphosphate-13c9-15n2-dilithium.html

Purity

99.5

Solubility

10 mM in DMSO

Smiles

O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]OP(OP(O[Li])(O[Li])=O)(O)=O)O[13C@H]1[15N]2[13C]([15NH][13C]([13CH]=[13CH]2)=O)=O

Molecular Weight

426.95

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Ashleigh S Paparella, et al. Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an SNi Mechanism and Ion Pair Transition State. ACS Chem Biol. 2022 Sep 16;17(9):2507-2518.|[3]Besada P, et al. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J Med Chem. 2006 Sep 7;49(18):5532-43.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-113359AS2/Uridine-5-diphosphate-13C9-15N2-dilithium-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-113359AS2/Uridine-5-diphosphate-13C9-15N2-dilithium-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

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