Estrone sulfate

Estrone sulfate is an endogenous metabolite present in Blood that can be used for the research of X-Linked Ichthyosis and Obesity[1][2][3].

Product Specifications

CAS Number

[481-97-0]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/estrone-sulfate.html

Solubility

10 mM in DMSO

Smiles

C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OS(=O)(O)=O)=C4)[C@@]3([H])CC1)C2=O

Molecular Formula

C18H22O5S

Molecular Weight

350.43

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Lykkesfeldt G, et al. Abnormal androgen and oestrogen metabolism in men with steroid sulphatase deficiency and recessive X-linked ichthyosis. Clin Endocrinol (Oxf) . 1985 Oct;23 (4) :385-93. |[2]Brind J, et al. Obese men have elevated plasma levels of estrone sulfate. Int J Obes. 1990 Jun;14 (6) :483-6. |[3]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.