3-Indolyl-β-D-glucuronide

3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in patients' plasma act as a new indicator of renal failure[1][2].

Product Specifications

CAS Number

[35804-66-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-indolyl-β-d-glucuronide.html

Solubility

10 mM in DMSO

Smiles

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CNC3=CC=CC=C23)=O

Molecular Formula

C14H15NO7

Molecular Weight

309.27

Precautions

H302, H315, H319, H335

References & Citations

[1]S Fujita, et al. [Evaluation of a new disk containing indoxyl-beta-D-glucuronide for rapid identification of Escherichia coli]. Rinsho Byori. 1996 Sep;44 (9) :895-8.|[2]S Agatsuma, et al. Indoxyl-beta-D-glucuronide and 3-indoxyl sulfate in plasma of hemodialysis patients. Clin Nephrol. 1996 Apr;45 (4) :250-6.