Epsilon-(gamma-glutamyl)-lysine
Product Specifications
UNSPSC Description
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/epsilon-gamma-glutamyl-lysine.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](N)CCC(NCCCC[C@H](N)C(O)=O)=O)=O
Molecular Weight
275.30
References & Citations
[1]Siegfried G Priglinger, et al. Potential Role of Tissue Transglutaminase in Glaucoma Filtering Surgery. Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3835-45.|[2]A M El Nahas, et al. Elevated Epsilon-(Gamma-Glutamyl)lysine in Human Diabetic Nephropathy Results From Increased Expression and Cellular Release of Tissue Transglutaminase.Nephron Clin Pract. 2004;97(3):c108-17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113089/Epsilon-gamma-glutamyl-lysine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113089/
Clinical Information
No Development Reported
CAS Number
17105-15-6
Curated Selection
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