Narasin (sodium)

Narasin sodium is a cationic ionophore and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin sodium has antimicrobial and anticancer activity[1].

Product Specifications

CAS Number

[58331-17-2]

UNSPSC

12352005

Hazard Statement

H302

Target

Antibiotic; Apoptosis; Bacterial; NF-κB; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/narasin-sodium.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@]2(O[C@](C)([C@]3([H])O[C@H]([C@](CC)(O)CC3)C)CC2)O[C@@]4(O[C@]([C@@H](C)C[C@H]4C)([H])[C@@H](CC)C([C@@H](C)[C@@H](O)[C@@H]([C@]5([H])O[C@@]([C@@H](C)C[C@@H]5C)([H])[C@@H](CC)C(O[Na])=O)C)=O)C=C1

Molecular Formula

C43H71NaO11

Molecular Weight

787.01

Precautions

P264-P270-P330-P501

References & Citations

[1]Miller SC, et al. Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. Biochem Pharmacol. 2010 May 1;79 (9) :1272-80.|[2]Ghada Bouguerra, et al. Stimulation of Eryptosis by Narasin. Cell Physiol Biochem. 2015;37 (5) :1807-16.