GSK8175
Product Specifications
UNSPSC Description
GSK8175 is a non-nucleoside polymerase (NS5B) inhibitor of hepatitis C virus (HCV). GSK8175 is a sulfonamide- N-benzoxaborole analog with low in vivo clearance across preclinical species and broad-spectrum activity against HCV replicons[1].
Target Antigen
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gsk8175.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(C=C2)=CC=C2F)OC3=CC(N(C4=CC(Cl)=C5C(COB5O)=C4)[S](C)(=O)=O)=C(C6CC6)C=C13)NC
Molecular Weight
568.81
References & Citations
[1]Chong PY, et al. Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J Med Chem. 2019;62(7):3254-3267.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112047/GSK8175-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112047/
Clinical Information
Phase 1
CAS Number
1423007-82-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Common beta Chain Antibody (OTI4H3) [DyLight 350]](https://cdn.genprice.uk/genprice/genprice2.png)
NBP2-70463UV 0.1 mL
Mouse Monoclonal Common beta Chain Antibody (OTI4H3) [DyLight 350]
Ask
View Details 