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IKK2-IN-3

Product Specifications

UNSPSC Description

IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].

Target Antigen

IKK

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ikk2-in-3.html

Purity

98.0

Solubility

DMSO : 10 mg/mL (ultrasonic;warming)

Smiles

O=C(C1=C(OCC2=CC=C(S(=O)(C)=O)C=C2)C=C(N3C4=CC(OC)=C(OC)C=C4N=C3)S1)N

Molecular Weight

487.55

References & Citations

[1]Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29(1):165-79.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111135/IKK2-IN-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111135/IKK2-IN-3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

916985-21-2

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