Displurigen
Product Specifications
UNSPSC Description
Displurigen (NSC375009) disrupts human embryonic stem cell pluripotency by targeting HSPA8. Displurigen inhibits ATPase activity of HSP70 (IC50 = 225 μM)[1].
Target Antigen
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
others
Assay Protocol
https://www.medchemexpress.com/displurigen.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(O)=C12)C=C(C3=CC=CC=C3)S2(=O)=O
Molecular Weight
286.30
References & Citations
[1]Yijie Geng, et al. A Chemical Biology Study of Human Pluripotent Stem Cells Unveils HSPA8 as a Key Regulator of Pluripotency. Stem Cell Reports. 2015 Dec 8;5(6):1143-1154.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111002/Displurigen-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111002/
Clinical Information
No Development Reported
CAS Number
96156-26-2
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