18A

18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env[1].

Product Specifications

CAS Number

[331261-50-8]

Product Name Alternative

HIV-1 inhibitor 18A

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/18a.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1/C=N/NC(NC2=CC=CC3=NSN=C23)=O

Molecular Formula

C14H11N5O2S

Molecular Weight

313.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Herschhorn A, et al. A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nat Chem Biol. 2014 Oct;10 (10) :845-52.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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