LG101506
Product Specifications
UNSPSC Description
LG101506 is a selective and orally active RXR modulator with a Ki of 2.7 nM for RXRα. LG101506 can be used for the research of type 2 diabetes and cancer[1][2].
Target Antigen
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lg101506.html
Solubility
10 mM in DMSO
Smiles
FC(F)COC1=C(C=C(C=C1/C(C)=C\C=C\C(C)=C\C(O)=O)C(C)(C)C)C(C)(C)C
Molecular Weight
420.53
References & Citations
[1]Gernert DL, et al. Design and synthesis of fluorinated RXR modulators. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3191-5.|[2]Cao M, et al. The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice. Cancer Prev Res (Phila). 2016 Jan;9(1):105-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108524/LG101506-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108524/
Clinical Information
No Development Reported
CAS Number
331248-11-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS761004-01 48 Well
Mouse Aryl hydrocarbon receptor nuclear translocator ELISA Kit
Ask
View Details 
MBS761004-02 96 Well
Mouse Aryl hydrocarbon receptor nuclear translocator ELISA Kit
Ask
View Details MBS761004-03 5x 96 Well
Mouse Aryl hydrocarbon receptor nuclear translocator ELISA Kit
Ask
View Details 
MBS761004-04 10x 96 Well
Mouse Aryl hydrocarbon receptor nuclear translocator ELISA Kit
Ask
View Details