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AC-VEID-CHO (TFA)

Product Specifications

UNSPSC Description

AC-VEID-CHO (TFA) is a peptide-derived caspase inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC50 values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. AC-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease[1].

Target Antigen

Caspase

Type

Peptides

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ac-veid-cho-tfa.html

Purity

98.7

Solubility

H2O : 1 mg/mL (ultrasonic;warming)

Smiles

OC(C(F)(F)F)=O.CC[C@@H]([C@@H](C(N[C@H](C=O)CC(O)=O)=O)NC([C@@H](NC([C@H](C(C)C)NC(C)=O)=O)CCC(O)=O)=O)C

Molecular Weight

614.57

References & Citations

[1]Robert Mintzer, et al. A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. PLoS One. 2012;7(1):e30376.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-108312A/AC-VEID-CHO-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-108312A/AC-VEID-CHO-TFA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Curated Selection

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