5-Iodo-A-85380 (dihydrochloride)
Product Specifications
UNSPSC Description
5-Iodo-A-85380 dihydrochloride is a selective ligand of nAChR. 5-Iodo-A-85380 dihydrochloride binds to α4β2 nAChRs in rat and human brain with Kds of 12 and 14 pM,respectively[1].
Target Antigen
nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-iodo-a-85380-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
IC1=CC(OC[C@@H]2CCN2)=CN=C1.[H]Cl.[H]Cl
Molecular Weight
363.02
References & Citations
[1]Mukhin AG, et al. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol. 2000 Mar;57(3):642-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107686/5-Iodo-A-85380-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107686/
Clinical Information
No Development Reported
CAS Number
1217837-17-6
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