LY-2087101
Product Specifications
UNSPSC Description
LY-2087101 is an allosteric potentiator of α7 nAChRs. LY-2087101 causes potentiation of agonist-evoked α7 responses by binding within the nAChR transmembrane region[1].
Target Antigen
nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly-2087101.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CSC=C1)C2=C(N=C(NC3=CC=C(F)C=C3)S2)C
Molecular Weight
318.39
References & Citations
[1]Gareth T Young, et al. Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14686-91.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107683/LY-2087101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107683/
Clinical Information
No Development Reported
CAS Number
913186-74-0
Curated Selection
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