Amitriptylinoxide
Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy[1].
Product Specifications
CAS Number
[4317-14-0]
Product Name Alternative
Equilibrin
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/amitriptylinoxide.html
Solubility
10 mM in DMSO
Smiles
C[N+](C)([O-])CC/C=C1C2=CC=CC=C2CCC3=C\1C=CC=C3
Molecular Formula
C20H23NO
Molecular Weight
293.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]J Tegeler, et al. Double-blind study of the therapeutic efficacy and tolerability of amitriptylinoxide in comparison with amitriptyline. Pharmacopsychiatry. 1990 Jan;23 (1) :45-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Available Sizes
Curated Selection
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