Lirequinil
Product Specifications
UNSPSC Description
Lirequinil (Ro 41-3696) is an orally active partial agonist of the benzodiazepine (BDZ) receptor. Lirequinil has the effect of promoting sleep[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lirequinil.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C[C@@H](OCC)CC1)C2=C3C4=C(C=CC(Cl)=C4)CCN3C(C(C5=CC=CC=C5)=C2)=O
Molecular Weight
448.94
References & Citations
[1]M Tsuboi, et al. Changes in mouse hippocampal EEG characteristics after oral administration of Ro 41-3696, nitrazepam, or zopiclone alone and in combination with ethanol. Pharmacology. 1994 Nov;49(5):278-85.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106917/Lirequinil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106917/
Clinical Information
Phase 2
CAS Number
143943-73-1
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