Ajoene
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].
Product Specifications
CAS Number
[92285-01-3]
UNSPSC
12352100
Hazard Statement
H225, H319, H336
Target
Apoptosis; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/ajoene.html
Concentration
21.33 mM * 200 μL in Ethyl acetate
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=S(C/C=C/SSCC=C)CC=C
Molecular Formula
C9H14OS3
Molecular Weight
234.40
Precautions
H225, H319, H336
References & Citations
[1]Taylor P, et al. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239 (2) :298-304. |[2]Ahmed N, et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res. 2001;21 (5) :3519-3523.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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