Sabcomeline

Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2].

Product Specifications

CAS Number

[159912-53-5]

Product Name Alternative

SB-202026; Memric

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sabcomeline.html

Solubility

10 mM in DMSO

Smiles

CO/N=C([C@@H]1C2CCN(CC2)C1)\C#N

Molecular Formula

C10H15N3O

Molecular Weight

193.25

References & Citations

[1]Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17 (2) :123-130. |[2]Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl) . 1998;138 (3-4) :275-282.