Tropatepine

Tropatepine is an orally active, anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents[2].

Product Specifications

CAS Number

[27574-24-9]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tropatepine.html

Purity

99.63

Solubility

10 mM in DMSO

Smiles

CN1[C@@H]2C/C(C[C@H]1CC2)=C3C4=CC=CC=C4SCC5=CC=CC=C\35

Molecular Formula

C22H23NS

Molecular Weight

333.49

References & Citations

[1]P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52 (7) :917-8.|[2]P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381 (1) :75-82.