Ambuphylline

Ambuphylline (Bufylline) is a bronchodilator. Ambuphylline is a theophylline derivative possibly acting through phosphodiesterase inhibition. Ambuphylline can be used for the research of asthma and other lung diseases[1].

Product Specifications

CAS Number

[5634-34-4]

Product Name Alternative

Bufylline

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ambuphylline.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(N(C)C(N1C)=O)N=CN2.OCC(C)(C)N

Molecular Formula

C11H19N5O3

Molecular Weight

269.30

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1] G Kagan, et al. Double-blind trial of a long-acting bronchodilator preparation ("Nethaprin Dospan") in bronchospastic disease. Curr Med Res Opin. 1976;4 (6) :436-41.