Capsaicin-d3

UNSPSC Description

Capsaicin-d3 is the deuterium labeled Capsaicin. Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects[1][2].

Target Antigen

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis;Autophagy;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

CC(C)/C=C/CCCCC(NCC1=CC(OC([2H])([2H])[2H])=C(C=C1)O)=O

Molecular Weight

308.43

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Anandakumar P, et al. Capsaicin provokes apoptosis and restricts benzo(a)pyrene induced lung tumorigenesis in Swiss albino mice. Int Immunopharmacol. 2013 Jun 6;17(2):254-259.|[3]Shin YH, et al. The Effect of Capsaicin on Salivary Gland Dysfunction. Molecules. 2016 Jun 25;21(7).|[4]McNamara FN, et al. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br J Pharmacol. 2005 Mar;144(6):781-90.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Clinical Information

No Development Reported

CAS Number

1217899-52-9

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