BRD4-IN-3
BRD4-IN-3 (compound 141) is a potent BRD4 inhibitor with an IC50 of 50 value of >1 µM[1].
Product Specifications
CAS Number
[1380087-86-4]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/brd4-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(N)C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=CC(Cl)=CC=C3C4=C1ON=C4C
Molecular Formula
C20H15Cl2N3O2
Molecular Weight
400.26
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Brian K. Albrecht, et al. Bromodomain inhibitors and uses thereof. WO2012075383A2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
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