3-Aminobenzoic acid (Standard)
Product Specifications
UNSPSC Description
3-Aminobenzoic acid (Standard) is the analytical standard of 3-Aminobenzoic acid. This product is intended for research and analytical applications. 3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects[1][2][3][4].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-aminobenzoic-acid-standard.html
Smiles
NC1=CC(C(O)=O)=CC=C1
Molecular Weight
137.14
References & Citations
[1]Tanaka M, et al. Exploring 3-Aminobenzoic Acid as a Therapeutic Dietary Component for Enhancing Intestinal Barrier Integrity in Ulcerative Colitis[J]. bioRxiv, 2024: 2024.08. 18.608525.|[2]Tanaka M, et al. P095 Accelerated degradation of gut barrier-protecting 3-aminobenzoic acid exacerbate colitis in Inflammatory Bowel Disease[J]. Journal of Crohn's and Colitis, 2024, 18(Supplement_1): i374-i374.|[3]Kumar A, et al. 3-Aminobenzoic Acid Analogues as a Novel GABA-at Inhibitors: Synthesis, Pharmacological Evaluation and Molecular Docking Studies[J]. Drug Discovery and Development, 2014, 1(2): 110-120.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-I0746R/3-Aminobenzoic-acid-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-I0746R/
CAS Number
99-05-8
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