Tabimorelin (hemifumarate)

Tabimorelin (NN703) hemifumarate is an orally active growth hormone (GH) secretagogue. Tabimorelin hemifumarate is also a potent inhibitor of CYP3A4 activity[1].

Product Specifications

CAS Number

[242143-80-2]

Product Name Alternative

NN703 (hemifumarate)

UNSPSC

12352005

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/tabimorelin-hemifumarate.html

Solubility

10 mM in DMSO

Smiles

CNC([C@@H](CC1=CC=CC=C1)N(C)C([C@H](N(C)C(/C=C/CC(C)(N)C)=O)CC2=CC3=CC=CC=C3C=C2)=O)=O.OC(/C=C/C(O)=O)=O

Molecular Formula

C32H40N4O3.1/2C4H4O4

Molecular Weight

586.72

References & Citations

[1]Zdravkovic M, et al. A clinical study investigating the pharmacokinetic interaction between NN703 (tabimorelin), a potential inhibitor of CYP3A4 activity, and midazolam, a CYP3A4 substrate. Eur J Clin Pharmacol. 2003 Feb;58 (10) :683-8.