Y11
Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397 and decreases tumor growth[1].
Product Specifications
CAS Number
[1086639-59-9]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/y11.html
Purity
98.34
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
OCC[N+]12C[N@](C3)C[N@](C[N@]3C2)C1.[Br-]
Molecular Formula
C8H17BrN4O
Molecular Weight
265.15
Precautions
H315, H319, H335
References & Citations
[1]Golubovskaya VM, et al. A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. J Med Chem. 2008 Dec 11;51 (23) :7405-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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