ICI 192605
Product Specifications
UNSPSC Description
ICI 192605 is a potent TXA2R (thromboxane A2 receptor) antagonist as cell signaling prostaglandin. ICI 192605 blocks contraction of isolated guinea pig trachea induced by U-46619[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ici-192605.html
Solubility
10 mM in DMSO
Smiles
OC(CC/C=C\C[C@@H]1[C@H](C(C=CC=C2)=C2O)O[C@H](C(C=CC=C3)=C3Cl)OC1)=O
Molecular Weight
402.87
References & Citations
[1]Brewster AG, et al. The synthesis of a novel thromboxane receptor antagonist 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid ICI 192605. Prostaglandins. 1988 Aug;36(2):173-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101236/ICI-192605-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101236/
Clinical Information
Phase 2
CAS Number
117621-64-4
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