T808

T808 is a tau-selective Alzheimer’s PET ligand. T808 is a type of imaging agent used in positron emission tomography (PET) scans. It is a radiotracer that is used to help visualize certain areas of the body, such as the brain, in order to diagnose and monitor various medical conditions[1].

Product Specifications

CAS Number

[1320211-61-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Tau Protein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/t808.html

Solubility

10 mM in DMSO

Smiles

FCCC1CCN(C2=NC3=NC4=CC=CC=C4N3C=C2)CC1

Molecular Formula

C17H19FN4

Molecular Weight

298.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Liu L, et al. [11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins. J Med Chem. 2021 Aug 26;64 (16) :12003-12021.