MAP4

MAP4 is a selective group III mGluR antagonist in some electrophysiological systems[1].

Product Specifications

CAS Number

[157381-42-5]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/map4.html

Solubility

10 mM in DMSO

Smiles

OC([C@@](C)(N)CCP(O)(O)=O)=O

Molecular Formula

C5H12NO5P

Molecular Weight

197.13

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Salt TE, Eaton SA. Distinct presynaptic metabotropic receptors for L-AP4 and CCG1 on GABAergic terminals: pharmacological evidence using novel alpha-methyl derivative mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vivo. Neuroscience. 1995 Mar;65 (1) :5-13.