Guanylyl Imidodiphosphate (trisodium)
Product Specifications
UNSPSC Description
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies[1][2][3].
Target Antigen
Adenylate Cyclase
Type
Biochemical Assay Reagents
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/guanylyl-imidodiphosphate-trisodium.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(NP(O)(O)=O)(O)=O)(O)=O)([H])N2C3=C(C(N=C(N3)N)=O)N=C2.[Na].[Na].[Na]
Molecular Weight
591.16
References & Citations
[1]Mitsunori Kawato, et al. Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. J Biol Chem. 2008 Jan 4;283(1):166-174.|[2]J Goldberg, et al. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell. 1998 Oct 16;95(2):237-48.|[3]C Gaudin, et al. Overexpression of Gs alpha protein in the hearts of transgenic mice. J Clin Invest. 1995 Apr;95(4):1676-83.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100767/Guanylyl-Imidodiphosphate-trisodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100767/
Clinical Information
No Development Reported
CAS Number
148892-91-5
Curated Selection
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