Dofetilide N-oxide
Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels[1][2].
Product Specifications
CAS Number
[144449-71-8]
Product Name Alternative
UK-116856
UNSPSC
12352005
Hazard Statement
H302-H312-H319
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dofetilide-n-oxide.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=CC=C(CC[N+](CCOC2=CC=C(NS(=O)(C)=O)C=C2)(C)[O-])C=C1)=O
Molecular Formula
C19H27N3O6S2
Molecular Weight
457.56
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Maisch B, et al. Pregnancy and cardiomyopathies. Herz. 2003 May;28 (3) :196-208.|[2]Snyders, D.J. and A. Chaudhary, High affinity open channel block by dofetilide of HERG expressed in a human cell line. Mol Pharmacol, 1996. 49 (6) : p. 949-55.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
