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Luteolin (monohydrate)

Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis[1].

Product Specifications

CAS Number

[6113-16-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; Keap1-Nrf2

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; NF-κB

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/luteolin-monohydrate.html

Purity

99.13

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=CC(O)=C(O)C=C2)OC3=C1C(O)=CC(O)=C3.O

Molecular Formula

C15H12O7

Molecular Weight

304.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Luo Y, et al. Luteolin cocrystals: Characterization, evaluation of solubility, oral bioavailability and theoretical calculation[J]. Journal of Drug Delivery Science and Technology, 2019, 50: 248-254.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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