BGSN3

BGSN3 is a good substrate for the SNAP-tag and H5 enzymes. The activities of SNAP-tag and H5 enzymes on BGSN3 are reasonable (IC50=17.8 and 10 μM, respectively) [1]. BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[2996069-91-9]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bgsn3.html

Concentration

10mM

Purity

98.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NCC1=CC=C(COC2=NC(N)=NC3=C2N=CN3)C=C1)CCCN=[N+]=[N-]

Molecular Formula

C17H19N9O2

Molecular Weight

381.39

References & Citations

[1]Merlo R, et al. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. J Enzyme Inhib Med Chem. 2021;36 (1) :85-97.