STING1 Antibody / TMEM173 / ERIS / MITA
TMEM173 (transmembrane protein 173), also called STING1, MITA and ERIS, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Product Specifications
UniProt
Q86WV6
Host
Mouse
Immunogen
A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the STING1 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Applications
WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the STING1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This STING1 antibody is available for research use only.
CAS Number
9007-83-4
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