CEBPZ Antibody
C/EBPZ (CCAAT/enhancer-binding protein Z), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBPZ stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBPZ is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBPZ promoter may be involved with acute myeloid leukemia. The C/EBPZ gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2.
Product Specifications
Specifications
Flow cytometry: 1-2ug/million cells, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q03701
Host
Mouse
Reactivity
Human
Immunogen
The protein domain of CEBPZ protein was used as the immunogen for the CEBPZ antibody.
Clonality
Monoclonal
Isotype
IgG2c
Clone
PCRP-CEBPZ-2D8
Applications
FACS, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CEBPZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CEBPZ antibody is available for research use only.
Storage Conditions
Aliquot the CEBPZ antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/cebpz-antibody-pcrp-cebpz-2d8-v4893
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CEBPZ antibody should be determined by the researcher.
CAS Number
9007-83-4
Location
Nucleus
Image Legend
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