CD147 / Emmprin / Basigin Antibody

Basigin is expressed more intensely on thymocytes than on mature peripheral blood T cells. It is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.