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CD147 / Emmprin / Basigin Antibody

Emmprin is expressed more intensely on thymocytes than on mature peripheral blood T cells. It is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

UniProt

P35613

Host

Mouse

Immunogen

Recombinant full-length human protein was used as the immunogen for the Emmprin antibody.

Clonality

Monoclonal

Isotype

IgG

Applications

IHC-P

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Emmprin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Emmprin antibody is available for research use only.

CAS Number

9007-83-4

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