BRG1 Recombinant Antibody / SMARCA4
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2A) and Brg-1 (also designated SNF2B) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/ SNF, including the NURF (nucleosome remodeling factor).
Product Specifications
UniProt
P51532
Host
Rabbit
Immunogen
A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the BRG1 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
ELISA, WB, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the BRG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BRG1 antibody is available for research use only.
CAS Number
9000-83-3
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