Desmoglein 3 Recombinant Antibody / DSG3
Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This mAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
Product Specifications
UniProt
P32926
Host
Mouse
Immunogen
A recombinant partial protein sequence (within amino acids 300-500) from the human protein was used as the immunogen for the DSG3 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the DSG3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DSG3 antibody is available for research use only.
CAS Number
9000-83-3
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