HER2 Recombinant Antibody / ErbB2 / Extracellular region
Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This mAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Product Specifications
UniProt
P04626
Host
Mouse
Immunogen
Recombinant protein encoding the extracellular domain of the human protein was used as the immunogen for the recombinant ErbB2 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant ErbB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant ErbB2 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/50551309/datasheet/v4468-20ug.pdf
CAS Number
9000-83-3
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Arabidopsis thaliana Uncharacterized mitochondrial protein AtMg00940 (AtMg00940)
Recombinant Arabidopsis thaliana Uncharacterized mitochondrial protein AtMg00940 (AtMg00940)
Recombinant Arabidopsis thaliana Uncharacterized mitochondrial protein AtMg00940 (AtMg00940)