TAG-72 Recombinant Antibody
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma
Product Specifications
UniProt
Not Known
Host
Rabbit
Immunogen
Purified TAG-72 protein was used as the immunogen for the TAG-72 antibody.
Clonality
Monoclonal
Isotype
IgG κ
Type
Recombinant
Applications
IHC-P
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the TAG-72 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TAG-72 antibody is available for research use only.
CAS Number
9000-83-3
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