FAN rabbit pAb
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009],
Product Specifications
Background
Gene ID
8439
UniProt
Q92636
Cellular Locus
Cytoplasm,cytosol,endomembrane system,extrinsic component of membrane,
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human FAN AA range: 147-197
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16527-1.pdf
Subcellular Location
Cytoplasm, cytosol, endomembrane system, extrinsic component of membrane
Gene ID (Human)
8439
SwissProt (Human)
Q92636
Available Sizes
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