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BG48

BG48 is a potent HDAC inhibitor. BG48 inhibits the enzymatic activity of HDAC1 and HDAC2[1].

Product Specifications

CAS Number

[1628784-53-1]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bg48.html

Purity

99.0900

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C=C1)/N=N/C2=CC=C(N(C)C)C=C2)NC3=C(N)C=CC(C4=CC=CS4)=C3

Molecular Formula

C25H23N5OS

Molecular Weight

441.55

References & Citations

[1]Reis SA, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes. Nat Chem Biol. 2016 May;12 (5) :317-23.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC2

Available Sizes

Curated Selection

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