HEPPS
HEPPS (EPPS) is a buffering agent with the useful pH range from 7.3 ~ 8.7. HEPPS reduces Aβ-aggregate-induced memory deficits and rescues cognitive deficits in mice. EPPS is orally active and penetrates the blood-brain barrier[1].
Product Specifications
CAS Number
[16052-06-5]
Product Name Alternative
EPPS
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β
Type
Biochemical Assay Reagents
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hepps.html
Purity
99.04
Solubility
H2O : 233.33 mg/mL (ultrasonic)
Smiles
O=S(CCCN1CCN(CCO)CC1)(O)=O
Molecular Formula
C9H20N2O4S
Molecular Weight
252.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim HY, et al. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nat Commun. 2015 Dec 8;6:8997.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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